Safety & side effects
XERMELO was safe and well tolerated in most patients
The most common side effects of XERMELO combined with somatostatin analog (SSA) therapy were nausea, headache, increase in hepatic enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, and fever.
XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
- Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.