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What to expect when starting XERMELO

In a clinical trial...

Many patients saw significant improvement within 12 weeks1

Some patients may start to see results within three weeks1

In the 12-week study, patients reported improvement in their diarrhea symptoms, primarily a reduction in bowel movement frequency. However, you could see results as early as three weeks.1

Continue to take XERMELO even if your symptoms improve

It’s important to continue taking XERMELO three times a day, every day. If you stop taking it, your symptoms could return, because Carcinoid Syndrome Diarrhea is a chronic condition.2

Take XERMELO three times a day, every day, with food1

XERMELO is a convenient pill that may help reduce diarrhea and the number of daily bowel movements when you take it regularly as directed.1 Also, people who take XERMELO with their SSA treatment may need fewer rescue SSA injections.1,3

3x daily with food 3x daily with food

Tips for taking XERMELO

  • Take XERMELO three times a day, every day, with food
  • Carry it with you while you’re on the go
  • Set reminders on your phone or sign up with a Clinical Nurse Educator to receive reminder text messages
  • Write down reminders in a journal or planner

Get started with XERMELO

Download a brochure to learn more about starting treatment with XERMELO.

Download brochure

How to get XERMELO

TerSera SupportSource has many resources to help

Get support

As little as $0 co-pay*

You could save if you have commercial insurance

See if you’re eligible

Starting on XERMELO?

Get one-on-one support to help you start, and stay, on treatment

Contact a nurse

*Eligibility criteria: Eligibility cannot be determined until all of the information submission requirements have been met by the healthcare professional, patient, and/or caregiver. Patients are not eligible for co-pay assistance if prescriptions are paid by any state or other federally funded programs, including, but not limited to, Medicare, Medicaid, Medigap, VA, DOD, TriCare, or where prohibited by law.

References

  1. XERMELO Prescribing Information. Deerfield, IL: TerSera Therapeutics LLC.
  2. Molina-Cerrillo J, Alonso-Gordoa T, Martínez-Sáez O, Grande E. Inhibition of peripheral synthesis of serotonin as a new target in neuroendocrine tumors. Oncologist. 2016;21(6):701-707.
  3. Kulke MH, Hörsch D, Caplin ME, et al. Telotristat ethyl, a tryptophan hydroxylase inhibitor for the treatment of carcinoid syndrome. J Clin Oncol. 2017;35(1):14-23.

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

 

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

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