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Getting started

How to get started with XERMELO

You need to take XERMELO 3 times a day, every day, with a meal or snack. That’s because food increases your body’s ability to absorb XERMELO.

Be sure to discuss any changes to your diet with your healthcare provider.

Icon of a fork and knife crosed over in an X formation with 3X above and DAILY on either side Icon of a fork and knife crosed over in an X formation with 3X above and DAILY on either side

In a clinical trial, many patients saw significant improvement at 12 weeks

Some patients may start to see results within 1 to 3 weeks

In the 12-week study, patients reported improvement in their diarrhea symptoms, primarily a reduction in bowel movement (BM) frequency. However, you could see results in 1 to 3 weeks. Individual results may vary. Learn more about the 12-week study.

Continue taking XERMELO as advised by your doctor, even if symptoms improve

It’s important to continue taking XERMELO three times a day, every day.

Randy C, a real XERMELO patient, standing with palm trees in the back
Randy C, a real XERMELO patient, standing with palm trees in the back

Hear from a real XERMELO patient

“The way XERMELO helps my CSD… hopefully it can help someone else.” –⁠ Randy C

CSD=carcinoid syndrome diarrhea.

Easy and convenient packaging — first dose and every dose

XERMELO comes in a monthly pack with 4 convenient blister packs (one per week).

When it comes to managing your CSD, XERMELO helps make it easy to remember and track every dose.

  • Carry it with you while you’re on the go
  • Set reminders on your phone, or sign up with a Clinical Nurse Educator to receive reminder text messages
  • Write down reminders in a journal or planner
Blister back of XERMELO

For illustration only.

Icon of a person from the neck down holding their painful stomach

Symptoms may return if you miss a dose of XERMELO.

Actor portrayals of a woman in a maroon-colored shirt talking with her doctor with brown hair wearing a striped button down and holding a notebook Actor portrayals of a woman in a maroon-colored shirt talking with her doctor with brown hair wearing a striped button down and holding a notebook Actor portrayals.

How to talk to your doctor about XERMELO

Complete a few questions and download your answers to create a helpful discussion guide for your next appointment.

Access and support

TerSera SupportSource has many resources to help

Get support

Co-pay support

You could pay as little as $0 co-pay* if you have commercial insurance

See if you’re eligible

Questions about treatment?

Our Clinical Nurse Educators can help answer your questions

Get dedicated support

* For eligible commercially insured patients, the co‑pay card is subject to an annual limit. You are not eligible if prescriptions are paid for by any state or other federally funded programs, including, but not limited to, Medicare or Medicaid, Medigap, VA, DOD, TRICARE, or where prohibited by law. Additional terms and conditions apply.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening 
abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report SUSPECTED ADVERSE REACTIONS, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Please see accompanying Full Prescribing Information.

Important Safety Information and Indication

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening 
abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report SUSPECTED ADVERSE REACTIONS, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Please see accompanying Full Prescribing Information.

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