How XERMELO helps

Get beyond the nearest bathroom with XERMELO

In a 12-week study, 89% of people taking XERMELO had a reduction in diarrhea frequency, compared to 69% of patients who were on somatostatin analog (SSA) treatment alone.1,2

12-week study nearly 9 out of 10 people taking xermelo has a reduction in diarrhea frequency

How XERMELO was studied

In TELESTAR, a major clinical study that led to XERMELO’s FDA approval, XERMELO plus SSA was compared with SSA alone in people with Carcinoid Syndrome.1 The study included 135 participants: 45 patients took XERMELO 250 mg plus SSA; 45 patients took XERMELO 500 mg* plus SSA; and 45 patients took SSA alone. All participants were followed for 12 weeks and recorded diarrhea frequency in a daily diary.1

In the study, XERMELO was generally considered safe and well tolerated in most people.

  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO

*The 500 mg dose was not FDA approved

Significant improvement in 12 weeks

Most patients see significant improvement in 12 weeks, and some patients may start to see results within 3 weeks1,2

Treating your Carcinoid Syndrome Diarrhea (CSD) with XERMELO plus SSA may take up to 12 weeks to reach the full effect.1 So, make sure to tell your doctor you want to stay on treatment for at least 12 weeks to get the best results.

Is XERMELO right for you?

If your current treatment isn’t allowing you to live your life the way you want, adding XERMELO to your treatment plan could make a big difference.

Learn more by downloading the XERMELO brochure and then use the discussion guide to talk to your doctor about how XERMELO could help.

Download brochure Download discussion guide

How XERMELO works

See the XERMELO study results in CSD

See the results

Ready to get started?

Tips for talking to your doctor and how to start on XERMELO

Get started

Have questions?

TerSera NurseSupport can help with every step

Contact a nurse

References

  1. Kulke MH, Hörsch D, Caplin ME, et al. Telotristat ethyl, a tryptophan hydroxylase inhibitor for the treatment of carcinoid syndrome. J Clin Oncol. 2017;35(1):14-23.
  2. XERMELO Prescribing Information. Deerfield, IL: TerSera Therapeutics LLC.

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

 

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

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