XERMELO® (telotristat ethyl) Carcinoid Syndrome Diarrhea Treatment

Your Life. Your Terms.

Take control of your Carcinoid Syndrome diarrhea with XERMELO

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XERMELO is different. It is the only medication that works to control the overproduction of serotonin, the primary cause of Carcinoid Syndrome diarrhea.

Share the impact of your symptoms with your doctor.

If your daily symptoms make it challenging to live a normal life despite somatostatin analog (SSA) treatment, you’re not alone. Talk to a doctor about treatment for Carcinoid Syndrome diarrhea with XERMELO.

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Is serotonin linked to Carcinoid Syndrome diarrhea?

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Important Safety Information and Indication

Important Safety Information and Indication

Important Safety Information

  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms
  • The most common side effects of XERMELO include nausea, headache, increase in hepatic enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, and fever
  • Talk to your doctor about all medicines you are taking as some may interact with XERMELO


XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

For more information about XERMELO, talk to your doctor or see Full Prescribing Information.

You may report an adverse event related to Lexicon products by calling 1-844-LEX-PHAR (1-844-539-7427)  (US only). If you prefer, you may contact the US Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where healthcare professionals and consumers can report serious problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit MedWatch or call 1-800-FDA-1088.