How XERMELO works
XERMELO plus SSA works in two different ways to reduce excess serotonin and manage CSD1-3
Even with somatostatin analog (SSA) therapy, you may still experience Carcinoid Syndrome Diarrhea (CSD).1 XERMELO targets serotonin in a different way.
SSA and XERMELO work together to reduce excess serotonin better than SSA alone3
Although SSA is a standard first treatment of CSD, many patients stop responding to SSAs over time.3 Escalating SSA dose or increasing frequency may not always be appropriate.
Unlike antidiarrheal medications, XERMELO directly targets the cause of CSD3
Taking over-the-counter medications or supplements may provide some temporary relief, but they won’t specifically target the cause of CSD.
- XERMELO Prescribing Information. Deerfield, IL: TerSera Therapeutics LLC.
- SANDOSTATIN® LAR Depot (octreotide acetate) Prescribing Information. Novartis Pharmaceuticals Corporation.
- Molina-Cerrillo J, Alonso-Gordoa T, Martínez-Sáez O, Grande E. Inhibition of peripheral synthesis of serotonin as a new target in neuroendocrine tumors. Oncologist. 2016;21(6):701-707.