This site is intended for US consumers
Find a Doc Doctor Discussion Guide

How XERMELO works

XERMELO pills + somatostatin analog (SSA) injections work together to reduce excess serotonin and manage carcinoid syndrome diarrhea (CSD)

SSA blocks release
of serotonin
outside the cell

Illustration of an open neuroendocrine tumor cell producing serotonin while somatostatin analogs are binding to the receptors outside of the cell, and XERMELO logo is inhibiting serotonin inside the cell Illustration of an open neuroendocrine tumor cell producing serotonin while somatostatin analogs are binding to the receptors outside of the cell, and XERMELO logo is inhibiting serotonin inside the cell

XERMELO reduces
overproduction
of serotonin
inside the cell

Even with SSA injections, you may still experience CSD. XERMELO targets a key cause of CSD, which is too much serotonin in the gut.

Actor portrayals of a woman in a maroon-colored shirt talking with her doctor with brown hair wearing a striped button down and holding a notebook Actor portrayals of a woman in a maroon-colored shirt talking with her doctor with brown hair wearing a striped button down and holding a notebook Actor portrayals.

How to talk to your doctor about XERMELO

Complete a few questions and download your answers to create a helpful discussion guide for your next appointment.

Create discussion guide

How XERMELO can help

See the XERMELO study results in CSD

See the results

Ready to get started?

Tips for taking and how to start on XERMELO

Get started

Questions about treatment?

Our Clinical Nurse Educators can help answer your questions

Get dedicated support

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening 
abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report SUSPECTED ADVERSE REACTIONS, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Please see accompanying Full Prescribing Information.

Important Safety Information and Indication

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Important Safety Information

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening 
abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report SUSPECTED ADVERSE REACTIONS, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for carcinoid syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

Please see accompanying Full Prescribing Information.

Attention

If you click “Continue” below, you will leave the current site. TerSera is not responsible for the privacy policy of any third-party websites. We encourage you to read the privacy policy of every website you visit.

Continue
Cancel

Healthcare Professionals

The information contained in this section of the site is intended for US Healthcare Professionals only. Click Continue if you are a US Healthcare Professional.

Continue
Cancel

Healthcare Professionals

The information contained in this section of the site is intended for US Healthcare Professionals only. Click Continue if you are a US Healthcare Professional.

Continue
Cancel

NPI lookup

To find your NPI number, please fill out the information below.

Fields marked with an asterisk (*) are required.

Enter your first name.
Enter your last name.
Select your state.

Search results

Select the entry with your name and address information.  

Name NPI number State ZIP Code  

No results found

Refine your search and try again.